Proteomics Portal
Welcome to the proteomics portal of CAPA. We are a core facility within the Institut de Recherches en Immunologie et Cancerologie (IRIC) equipped with industry-leading high resolution Orbitrap instrumentation. Our expertise includes protein identification, intact protein analysis, post-translational modifications (PTMs), and quantitative differential profiling. Learn more about our technology and applications by clicking on the links below.
Time-resolved Phosphoproteome Analysis of Paradoxical RAF Activation Reveals Novel Targets of ERK
Peter Kubiniok, Hugo Lavoie, Marc Therrien, and Pierre Thibault.
Mol Cell Proteomics. 2017 Apr;16(4):663-679
Machine Learning of Global Phosphoproteomic Profiles Enables Discrimination of Direct versus Indirect Kinase Substrates
Evgeny Kanshin, Sebastien Giguere, Cheng Jing, Mike Tyers, and Pierre Thibault.
Mol Cell Proteomics , 16: 10.1074/mcp.M116.066233, 786–798, 2017
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification
Frederic Lamoliatte, Francis P. McManus1,, Ghizlane Maarifi, Mounira K. Chelbi-Alix & Pierre Thibault
Nature Communications 2017 Jan 18;8:14109. doi: 10.1038
CLMSVault: A Software Suite for Protein Cross-Linking Mass-Spectrometry Data Analysis and Visualization
Mathieu Courcelles, Jasmin Coulombe-Huntington, Émilie Cossette, Anne-Claude Gingras, Pierre Thibault, and Mike Tyers,
J. Proteome Res. 2017, 16, 2645−2652